E matlafatsoa ke Xi'an Rainbow Bio-Tech Co.,Ltd, Moqapi ea ka Sehloohong oa Phytochemical
1. Kenyelletso ea Isoquercetin
Isoquercetin (CAS No. 482-35-9), flavonol glycoside e tsoang ho quercetin, ke motsoako oa tlhaho oa polyphenolic o fumanoang limela tse sa tšoaneng, ho akarelletsa le eiee, liapole, buckwheat, le litlama tsa meriana tse kang Ginkgo biloba le Hippophae rhamnoides. E le motsoako oa bohlokoa oa bioactive, e fumane tlhokomelo e kholo indastering ea meriana, phepo e nepahetseng, lijo le litlolo ka lebaka la thepa ea eona e matla ea antioxidant, anti-inflammatory le therapeutic. Tokomane ena e fana ka kakaretso e felletseng ea isoquercetin, ho kenyeletsoa sebopeho sa eona sa lik'hemik'hale, maemo a boleng, lits'ebetso tse fapaneng, le botsebi ba theknoloji ba [Lebitso la K'hamphani ea Hao] ho fana ka tharollo ea premium isoquercetin.
2. Litšobotsi tsa Motheo tsa Isoquercetin
2.1 Sebopeho sa Lik'hemik'hale le Thepa
● Foromo ea Molek'hule:C₂₁H₂₀O₁₁
● Boima ba Molek'hule:464.38 g/mol
● Sebopeho sa Lik'hemik'hale:Flavonol aglycone (quercetin) e hokahantsoeng le molek'hule ea tsoekere ka bond ea glycosidic (3-O-glucoside).
● Ponahalo ea 'Mele:Phofo ea kristale e mosehla e nang le tatso e babang.
● Sollubility:Ho qhibiliha hanyenyane ka metsing; qhibilihang ka har'a ethanol, methanol le DMSO.
●Botsitso:E utloa bohloko ho khanya le mocheso; e tsitsitseng tlas'a maemo a polokelo a laoloang (2-8°C).
2.2 Mehloli ea Tlhaho
Isoquercetin e fumaneha ka bongata ho:
●Limela:Buckwheat (Fagopyrum esculentum), eie (Allium cepa), liapole (Malus domestica), le monokotsoai (mohlala, blueberries, cranberries).
●Meriana ea Meriana:Ginkgo biloba (makhasi), Hypericum perforatum (St. John's Wort), le Sophora japonica (sefate sa Japanese pagoda).
●Lijo:Tee e tala, veine e khubelu, le mefuta e itseng ea mahe a linotši.
2.3 Bioactivity le Mechanis of Action
● Mosebetsi oa Antioxidant:E senya li-radicals tsa mahala (mohlala, hydroxyl, superoxide) 'me e thibela khatello ea oxidative ka ho phahamisa pontšo ea Nrf2.
● Thibelo ea ho ruruha:E hatella li-cytokine tsa pro-inflammatory (TNF-α, IL-6) le ho thibela ts'ebetso ea tsela ea NF-κB.
●Cardioprotective:E ntlafatsa ts'ebetso ea endothelial, e fokotsa khatello ea mali, 'me e thibela ho kopana ha platelet.
● Anticancer:E kenya apoptosis liseleng tsa mofetše (mohlala, matsoele, matšoafo, colorectal) le ho thibela angiogenesis.
● Neuroprotective:E sireletsa khahlanong le mafu a neurodegenerative (mohlala, Alzheimer's, Parkinson's) ka ho fokotsa tšenyo ea oxidative le ho ruruha.
3. Boleng ba Sehlahisoa: Premium-Grade Isoquercetin ka Xi'an Rainbow Bio-Tech CO.,Ltd
3.1 Bohloeki le Maemo a Tlhahiso
●Bohloeki:≥98% (tlhahlobo ea HPLC, USP/EP/BP e lumellana).
● Heavy Metals:≤10 ppm (ICP-MS e lekoa).
● Tšireletso ea Microbiological:E lumellana le USP <61> le <62> (palo ea palo ea poleiti ≤1000 CFU / g, tomoso / hlobo ≤100 CFU / g, ha ho E. coli kapa Salmonella).
● Solvent Residus:≤0.5% (ethanol, methanol; GC-MS e lekoa).
3.2 Mokhoa oa Tlhahiso
Xi'an Rainbow Bio-Tech Co., Ltd e sebelisa mokhoa oa ho hula le oa tlhoekiso o sebetsang hantle, o bonolo oa tikoloho le oa tlhoekiso:
1.Raw Material Sourcing:Li-extracts tsa limela tsa maemo a holimo tse tsoang linthong tse hlaha.
2.Tlosa:Ultrasound-assisted extraction (UAE) ka li-solvents tsa boemo ba lijo (ethanol / metsi).
3.Tlkiso:Column chromatography (silica gel/ODS) le HPLC ea boitokisetso bakeng sa ho itšehla thajana ho phahameng.
4. Tlhahiso:Ho fafatsa-ho omisa kapa ho omisa ka leqhoa ho hlahisa phofo e ntle kapa li-granules tse nang le boholo ba likaroloana (10-100 μm).
3.3 Tsamaiso ea Boleng (QC) System
●Lilaboratoriamo tsa Boemo ba Bonono:E na le HPLC, LC-MS, NMR, le GC-MS bakeng sa tlhahlobo e matla.
●Batch Traceability:Litokomane tse felletseng ho tloha ho thepa e tala ho isa sehlahisoa sa ho qetela (ISO 22000: 2018 e lumellana).
● Setifikeiti:Setifikeiti sa Kosher, Halal, le FSSC22000.
4. Likopo tsa Isoquercetin
4.1 Indasteri ea Meriana
●Ntšetso-pele ea Lithethefatsi:
● Bahlaseli ba Mofets'e:E entsoe ka litlhare tse kopaneng (mohlala, ka cisplatin) ho matlafatsa cytotoxicity le ho fokotsa litlamorao.
●Lithethefatsi tsa pelo:E sebelisoa litlhare tsa antihypertensive le anticoagulant (mohlala, matlapa a coenzyme Q10 + isoquercetin).
● Lithethefatsi tsa Neuroprotective:E kenyelelitsoe ho prototypes ea kalafo ea Alzheimer (mohlala, donepezil + isoquercetin capsules).
4.2 Tlatsetso ea Phepo le Lijo
●Melemo ea Bophelo bo Botle:
● Tšehetso ea 'mele ea ho itšireletsa mafung, ho thibela botsofali, le taolo ea metabolism (mohlala, taolo ea tsoekere ea mali).
● Bophelo bo botle ba manonyeletso (bo fokotsa ho ruruha ha masapo).
●Lihlahisoa tsa Maraka:
● Li-Capsules (200-500 mg isoquercetin / letsatsi).
●Lino tse sebetsang (mohlala, tee e tala e tšetsoeng isoquercetin).
4.3 Indasteri ea Lijo le Lino
● Lisebelisoa tse sebetsang:
● Tšireletso ea tlhaho ea tlhaho (e eketsa nako ea bophelo ka ho sebelisa lithibela-mafu).
● Ho matlafatsa phepo e nepahetseng (ho matlafatsa antioxidant ka lero, lijo tse bobebe).
4.4 Litlolo le Tlhokomelo ea Botho
● Bophelo bo Botle ba Letlalo:
● Tšireletso ea Antioxidant khahlanong le tšenyo ea UV.
● Ho thibela botsofali (khothatso ea collagen synthesis, ho fokotsa mats'oao).
● Anti-inflammatory bakeng sa letlalo le utloang bohloko (mohlala, eczema, rosacea).
●Meetso:
●Serum, litlolo, le limaske (0.5-2% isoquercetin).
4.5 Meriana ea Liphoofolo
● Bophelo bo Botle ba Liphoofolo:
● Ho thibela ho ruruha ha liphoofolo tse ruuoang lapeng (mohlala, osteoarthritis lintjang).
● Tšehetso ea 'mele ea ho itšireletsa mafung ka mehlape (e fokotsa tšenyo ea oxidative e amanang le khatello ea kelello).
5. Xi'an Rainbow Bio-Tech Co.,Ltd – Molekane oa Hao eo U Mo tšepang ho Phytochemical Innovation
5.1 Kakaretso ea Khampani
E thehiloe ka 2010, Xi'an Rainbow Bio-Tech Co., Ltd ke moetapele oa lefats'e ka bophara lipatlisisong, nts'etsopele le tlhahiso ea li-bioactive tse thehiloeng limela. Ka setsi se netefalitsoeng sa 20,000 m² GMP le sehlopha sa bo-ramahlale ba fetang 150, re ipabola ho:
● Ho ntšoa ka mokhoa o ikhethileng le tlhoekiso ea li-flavonoids, li-alkaloids, le polyphenols.
● Tlhahiso ea konteraka (CMO) bakeng sa bareki ba meriana le phepo e nepahetseng.
● Metsoako ea thepa (mohlala, nanoecapsulated isoquercetin bakeng sa bioavailability e ntlafalitsoeng).
5.2 Bokhoni ba R&D
● Tšebelisano:Tšebelisano 'moho le liunivesithi tse etellang pele (mohlala, Univesithi ea Shaanxi Normal) le litsi tsa lipatlisiso.
●Patents:12+ litokelo tsa molao mabapi le ho ntšoa ha isoquercetin, tlhahiso le lits'ebetso.
5.3 Bokhabane ba Tlhahiso
●Boemo:Lithane tse 10 tsa metric / selemo tsa isoquercetin (95-99% bohloeki).
●Moshoelella:Tlhahiso ea litšila e se nang litšila ka mokhoa oa ho sebelisa li-solvents tse koetsoeng.
● phihlello ea Lefatše:E sebelelitse bareki ba 200+ linaheng tse 30+ (mohlala, USA, EU, Japan, Australia).
5.4 Litšebeletso tsa Bareki
● Tšehetso ea Theknoloji:Tokisetso ea lintlha tse ikhethileng (mohlala, DMF, CEP).
● Tumellano ea Taolo:Ts'ehetso e felletseng bakeng sa litlatsetso tsa FDA, EFSA, le TGA.
● Likhetho tsa ho paka:Liphutheloana tse tloaelehileng (mekotla ea foil ea aluminium, meropa ea HDPE) e nang le tšireletso ea mongobo / khanya.
6. Qetello: Isoquercetin - Tharollo ea Tlhaho bakeng sa Mathata a Kajeno
Isoquercetin's bioactivity e feto-fetohang e e beha e le motsoako oa mantlha litabeng tsa bophelo bo botle, phepo e nepahetseng le tlhokomelo ea motho. Xi'an Rainbow Bio-Tech Co., Ltd Boitlamo ba boleng, boqapi, le botsitso bo netefatsa hore lihlahisoa tsa rona tsa isoquercetin li fihlella litekanyetso tse phahameng ka ho fetisisa tsa lefats'e. Ebang ke molemong oa nts'etsopele ea lithethefatsi, li-supplement tsa lijo, kapa litlolo tsa litlolo, tharollo ea rona e matlafatsa liindasteri ho sebelisa bokhoni ba tlhaho bakeng sa bophelo bo botle.
Kopana matsoho le Xi'an Rainbow Bio-Tech Co.,Ltd – moo saense e kopanang le tlhaho.
Nako ea poso: Apr-01-2025